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Route 66 stops in Missouri

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Two Olde Crows Antique Mall

1. Two Olde Crows Antique Mall

100 Rocky Creek Road, Cuba, MO

A 9,000 sq ft antique mall in Cuba, MO with 100+ vendors packed with vintage Route 66 treasures.

Shops & Markets Antique / Vintage
Frisco's Grill & Pub

2. Frisco's Grill & Pub

121 S Smith St, Cuba, MO

Local bar and grill with classic American fare and Route 66 vibes.

Restaurants & Food Bar & Grills Burgers Casual Dining Family-Friendly Sandwiches
Cuba Bakery & Deli

3. Cuba Bakery & Deli

702 S Franklin St, Cuba, MO

Freshly baked bread, deli sandwiches, and a friendly small-town atmosphere.

Restaurants & Food Bakeries Cafés Delis Desserts Sandwiches
Best Budget Inn LLC

4. Best Budget Inn LLC

13008 Hwy 96 E, CARTHAGE, MO

1955 Carthage Route 66 motel by Kellogg Lake Park offering quiet, comfy stays

Lodging Motels
Boots Court Motel

5. Boots Court Motel

107 S Garrison Ave, Carthage, MO

Restored 1940s-style motor court known for its retro charm and neon sign.

Lodging Historic Motels & Hotels Hotels Motels Unique Stays
TaquerÃ

6. TaquerÃ

2406 Grand Ave, Carthage, MO

Authentic Mexican food, snacks, desserts, and artisan ice cream.

Restaurants & Food Bakeries Casual Dining Family-Friendly Ice Cream / Sweets Mexican
Iggy's Diner

7. Iggy's Diner

2400 Grand Ave, Carthage, MO

Classic American diner serving breakfast and comfort food.

Restaurants & Food Casual Dining Diners Family-Friendly
Cuba Route 66 Shield Monument

8. Cuba Route 66 Shield Monument

913 Old Rte 66, Cuba, MO

Oversized Route 66 shield monument — a classic roadside photo stop.

Murals & Monuments Route 66 3D Monuments
Bette Davis Mural

9. Bette Davis Mural

501 E Washington Blvd, Cuba, MO

A Cuba, Missouri mural that captures a surprising and unforgettable encounter between Hollywood legend Bette Davis and a local photographer.

Murals & Monuments Historic Murals
Al West Mural

10. Al West Mural

201 E Washington St, Cuba, MO

A Cuba, Missouri mural honoring former mayor Al West Sr., whose leadership helped transform the town into a modern city.

Murals & Monuments Historic Murals
The River Mural

11. The River Mural

110 N Franklin St, Cuba, MO

A Cuba, Missouri mural celebrating the region’s deep connection to its rivers, from early Native American travel to modern-day floating culture.

Murals & Monuments Historic Murals
Amelia Earhart Mural

12. Amelia Earhart Mural

100 N Madison St, Cuba, MO

Mural commemorating that Amelia Earhart made a forced emergency landing in Cuba on September 4, 1928.

Murals & Monuments Historic Murals
The Fourway Mural

13. The Fourway Mural

102 W Washington Blvd, Cuba, MO

A three-panel mural in Cuba, Missouri celebrating a restored 1932 Phillips 66 station and the legacy of the Wallis family.

Murals & Monuments Historic Murals
John Manson Munro House

14. John Manson Munro House

102 W Washington St,, Cuba, MO

Late Victorian home on the National Register; a landmark of Cuba's early prosperity.

Landmarks & Historic Sites Historic Buildings/Structures
The Apple Mural

15. The Apple Mural

511 W Washington St, Cuba, MO

Mural Commerating that rom 1895-1920, Cuba was the largest producer, processor, and distributor of apples in the state of Missouri.

Murals & Monuments Historic Murals
A Day in the Cooperage Mural

16. A Day in the Cooperage Mural

511 W Washington St, Cuba, MO

A Day in the Cooperage Mural that honors McGinnis Wood Products' 50th anniversary.

Murals & Monuments Historic Murals
Old Cuba City Jail

17. Old Cuba City Jail

306 Southwest Main St, Cuba, MO

Preserved stone jail from Cuba’s early days—perfect for historic photo ops.

Landmarks & Historic Sites Historic Buildings/Structures Route 66 Historic Properties
The Millworks Mural

18. The Millworks Mural

156 N Smith St, Cuba, MO

A Cuba mural depicting craftsmen inside the 1948 Roberts-Judson Sheetmetal & Millworks building Cuba, MO, part of the city's Route 66 Mural City collection.

Murals & Monuments Historic Murals
People's Bank Mural

19. People's Bank Mural

506 W Washington St, Cuba, MO

Local banker A.J. Barnett eventual People Bank President who also owned Cuba's first Model T.

Murals & Monuments Historic Murals
Meeting In Missouri Mural

20. Meeting In Missouri Mural

108 S Buchanan St, Cuba, MO

A Cuba, Missouri mural depicting the historic meeting between the Osage Nation and early French settlers.

Murals & Monuments Historic Murals
Prosperity Corner Mural

21. Prosperity Corner Mural

103 S Smith St, Cuba, MO

Prosperity Corner Mural showing citizensmeeting to do business, and pass the time of day at H.H. Tieman’s General Merchandise Store.

Murals & Monuments Historic Murals
Civil War Murals

22. Civil War Murals

112 S Buchanan St, Cuba, MO

A series of murals in Cuba, Missouri depicting Civil War events from General Sterling Price’s 1864 campaign through the region.

Murals & Monuments Historic Murals
Harry Truman Mural

23. Harry Truman Mural

609 W Washington St, Cuba, MO

The mural commemorates Harry Truman's 1940 Senate campaign stop in Cuba.

Murals & Monuments Historic Murals
Greetings from Cuba MO Postcard Mural

24. Greetings from Cuba MO Postcard Mural

606 W Washington St, Cuba, MO

A vibrant Route 66 mural in Cuba, Missouri styled like a classic “Greetings Fromâ€

Murals & Monuments Route 66 Murals
World's 2nd Largest Rocking Chair

25. World's 2nd Largest Rocking Chair

5956 State Hwy ZZ, Cuba, MO

Massive roadside rocking chair along Route 66, once billed as the world’s largest and now a popular photo stop.

Roadside Attractions Giant Objects
19 Drive-In

26. 19 Drive-In

5853 MO-19, Cuba, MO

A beloved 1955 Route 66 drive-in theater that entertained generations of locals and travelers before closing.

Roadside Attractions
Viva Cuba Mural Project

27. Viva Cuba Mural Project

102 S Filmore, Cuba, MO

Collection of outdoor murals depicting local and national history.

Murals & Monuments Route 66 Murals
Rockwood Court Sign

28. Rockwood Court Sign

2200 W College St, Springfield, MO

Surviving sign from the historic Rockwood Court motor court on Route 66.

Classic Signs & Neon Business Signs Motel Signs
Wagon Wheel Sign

29. Wagon Wheel Sign

901 E Washington St, Cuba, MO

Historic Wagon Wheel Motel sign associated with one of the oldest continuously operating Route 66 motels.

Classic Signs & Neon Business Signs Classic Neon Motel Signs
Uranus Missouri Towne Center

30. Uranus Missouri Towne Center

14400 State Hwy Z, St Robert, MO

A quirky Route 66 family fun destination in the Missouri Ozarks, famous for its fudge and roadside charm.

Shops & Markets General Stores
The Gateway Arch

31. The Gateway Arch

11 N Fourth St, St. Louis, MO

Iconic 630-foot monument symbolizing westward expansion.

Murals & Monuments Sculptural Monuments
Neon Museum of Saint Louis

32. Neon Museum of Saint Louis

3537 Chouteau Ave, St. Louis, MO

Collection of restored neon signs from mid-century STL.

Museums Specialty / Niche Museums
Moonrise Hotel

33. Moonrise Hotel

6177 Delmar Blvd, St. Louis, MO

Boutique hotel with space-themed decor and rooftop bar.

Lodging Hotels
Missouri History Museum

34. Missouri History Museum

5700 Lindell Blvd, St. Louis, MO

Museum showcasing Missouri’s diverse history, including Route 66 and STL heritage exhibits.

Museums Regional Museums
Donut Drive-In

35. Donut Drive-In

6525 Chippewa St, St. Louis, MO

Classic roadside donut shop serving fresh donuts and coffee since 1952.

Restaurants & Food Desserts
Ted Drewes Frozen Custard

36. Ted Drewes Frozen Custard

6726 Chippewa St, St. Louis, MO

Famed frozen custard stand and Route 66 institution since the 1930s.

Restaurants & Food Desserts
Spencer's Grill

37. Spencer's Grill

223 S. Kirkwood Rd., Kirkwood, MO

Historic diner known for breakfast and burgers, now closed.

Restaurants & Food Diners
National Museum of Transportation

38. National Museum of Transportation

2933 Barrett Station Rd, St. Louis, MO

One of the largest collections of transportation vehicles in the world.

Museums Transportation / Automotive Museums
Big Chief Roadhouse

39. Big Chief Roadhouse

17352 Manchester Rd, Wildwood, MO

Rustic steakhouse and tavern-style dining in a historic 1920s Route 66 stop.

Restaurants & Food Steakhouses
Beacon Car Wash

40. Beacon Car Wash

675 E Osage St, Pacific, MO

Retro-themed car wash on Route 66.

Roadside Attractions Quirky Stops
Gardenway Motel Sign

41. Gardenway Motel Sign

2827 MO-100, Villa Ridge, MO

Historic Route 66 motel sign in Villa Ridge.

Classic Signs & Neon Motel Signs
Sunset Motel - MO

42. Sunset Motel - MO

976 Osage Villa Ct, Villa Ridge, MO

Another abandoned Route 66 motel—sun-faded signage and overgrown lots echo its former glory.

Lodging Motels
Gardenway Motel

43. Gardenway Motel

1340 Historic US 66, Villa Ridge, MO

Deserted but iconic roadside motel—now a ghostly marker of Route 66's golden era.

Lodging Motels
Shamrock Court

44. Shamrock Court

101 Shamrock, Sullivan, MO

Once a motor court for Route 66 travelers, now a crumbling relic of mid-century roadside stays.

Lodging Historic Motels & Hotels
Cuba Inn

45. Cuba Inn

246 State Hwy P, Cuba, MO

Small local motel offering convenient overnight lodging for Route 66 travelers.

Lodging Motels
Shelly's Smashburger

46. Shelly's Smashburger

5885 Highway 19, Cuba, MO

Roadside burger spot near the I-44 exit serving smashburgers and quick bites.

Restaurants & Food Burgers Casual Dining
Huddle House

47. Huddle House

28 State Hwy P, Cuba, MO

Casual diner-style restaurant serving breakfast, lunch, and dinner just off Route 66 in Cuba.

Restaurants & Food Family-Friendly
Cuba Visitors Center

48. Cuba Visitors Center

71 State Hwy P, Cuba, MO

Cuba's welcome center with maps, brochures, and Route 66 info.

Community & Visitor Services Visitor Centers
Missouri Hick BBQ

49. Missouri Hick BBQ

913 E Washington St, Cuba, MO

Rustic BBQ joint known for smoked meats, sweet tea, and Route 66 ambiance.

Restaurants & Food BBQ
East Sun

50. East Sun

617 N Franklin St B,, Cuba, MO

Casual local restaurant in Cuba offering quick meals and everyday comfort food.

Restaurants & Food Casual Dining Chinese
Riviera Maya Mexican Restaurant

51. Riviera Maya Mexican Restaurant

604 E Main St, Cuba, MO

Colorful Mexican restaurant serving authentic dishes in a festive setting.

Restaurants & Food Mexican
Shelly's Route 66 Cafe

52. Shelly's Route 66 Cafe

402 S Lawrence St, Cuba, MO

Homestyle meals and friendly service in a Route 66-themed diner.

Restaurants & Food Casual Dining
East Office Bar & Grill

53. East Office Bar & Grill

406 E Washington Blvd, Cuba, MO

Local Route 66 bar and grill in downtown Cuba known for casual food and a relaxed local crowd.

Restaurants & Food Bar & Grills Casual Dining
Rich's Famous Burgers

54. Rich's Famous Burgers

102 W Washington St, Cuba, MO

Popular downtown Cuba burger stop known for hearty burgers along historic Route 66.

Restaurants & Food American Burgers Casual Dining Diners Family-Friendly
Hayes Family Shoe Store

55. Hayes Family Shoe Store

103 S Smith St, Cuba, MO

A long-standing Cuba, Missouri shoe store known for its wide selection and a unique display featuring shoes worn by Robert Wadlow, the tallest man in recorded history.

Shops & Markets Apparel / Clothing
Fanning Outpost General Store

56. Fanning Outpost General Store

5957 State Hwy ZZ, Cuba, MO

Route 66 roadside general store and gift shop next to the World’s 2nd Largest Rocking Chair.

Roadside Attractions General Stores
Totem Pole Trading Post

57. Totem Pole Trading Post

1413 Martin Springs Dr, Rolla, MO

Historic Route 66 souvenir and gas stop still operating.

Shops & Markets Trading Posts
Uranus Playground

58. Uranus Playground

14400 State Hwy Z, St Robert, MO

An experience the whole family will enjoy with attractions to entertain all ages with a sense of humor, fun and adventure.

Family & Entertainment Attractions Family Fun Centers
Uranus Fudge Factory & General Store

59. Uranus Fudge Factory & General Store

14400 Highway Z, St Robert, MO

Roadside attraction with candy, museum displays, quirky gifts, and selfie spots.

Roadside Attractions Quirky Stops
Roubidoux Bridge

60. Roubidoux Bridge

107 Route 66, Waynesville, MO

Bridge over Roubidoux Creek along Route 66.

Landmarks & Historic Sites Bridges